Karma Upon Death by Scrabble - 960 Words

Tyrone Gibson Mr.Borrelli Sunday, July 7, 2013 Karma Upon Death By Scrabble Karma. What is karma? Is it a part of life? Is it what helps us make decisions? Or is it the balance of life and everyone living in it? In Charlie Fish’s story Death By Scrabble karma is the main theme. This fictional story is about a husband and his wife playing Scrabble, a game in which players earn points for the words made by them with available letters. The story narrates how the words in the game reflect the practical life of the†¦show more content†¦Ã¢â‚¬Å"I don’t believe it- it can’t be Tilo 3 a coincidence. The letters made it happen. I played the word explodes...and the air conditioning unit exploded† (page 3) with this mindset of the husband he reveals the irony and the reality in the story for the reader. A big part of irony in the story is how his cousin â€Å"Harold swallowed a bee when he was nine, his throat swelled up and he died.† (page 1) Then towards the end of the story he chokes on a â€Å"b† just like his cousin and dies. The greatest irony in the story is the fact that throughout the whole time the husband is playing scrabble trying to figure out which words he can spell out to kill his wife, but what he doesn’t know is that his wife is playing the same game. And ironically she ends up winning. Irony in this story best illustrates Karma. Finally the use of these literary terms helped create the theme of this story. The suspense kept the reader wanting to know what will happen to the wife. will he kill her? Foreshadowing in this story is also another huge part in showing karma, when heShow MoreRelatedAlcohol and Spiritual Deadlock--John Berryman Essay2633 Words   |  11 Pageshis introduction to John Berrymans unfinished work Recovery, about his efforts to recover from alcoholism, Saul Bellows asserts that the act of writing poetry killed Berryman, and alcohol helped fuel the writing process: Inspiration contained a death threat. He would, as he wrote the things he waited and prayed for, fall apart, (Recovery xii). During his career as a poet, he was diseased with alcoholism and suffered from extreme lapses of anxiety. Berryman wrote a majority of the Dream Songs

Essay on Measuring Customer Satisfaction in Government...

Being in the government sector the research for customer satisfaction was focused on governmental agencies and the aspects associated with those agencies. Most citizens have a preconceived idea about government agencies and I wanted to see if those preconceived ideas were based on real experiences. This was done by researching and finding results either supporting or contradicting this notion. According to Tom Schoop the government does as well as any big company as far as customer satisfaction. (Schoop 2006) I work for a contractor, ResCare that is assigned by the Dallas County Texas Workforce Board to operate the Dallas County Workforce Centers and run the associated state and federal programs assigned to the Dallas County Workforce†¦show more content†¦This was best illustrated with the failure of the Healthcare Act’s website’s inability to handle this increasing demand. (ACSI Federal Government Report 2013, 2014) The best way for the federal government to a ddress these customer issues is improve access to the websites. Encourage agencies to communicate with the customer and learn accessing behaviors and functions that would increase the ability to access the website efficiently. The second area is in the state of Texas’ customer satisfaction with the Texas Workforce Commission. As mentioned previously, the recipients of unemployment benefits (UI) have only two options to access their benefits or their profiles as well as file claims. The 1-800 phone number or through the Texas Workforce Commission’s (TWC) website. This area I have over three years’ experience and have observed customer’s reactions as well as read customer surveys. This has increased confusion in older and first-time recipients. Many of the older recipients received UI benefits previously when they would visit a TWC office to file their claim and receive benefits. This has all been move to the phone or the Internet so they require additional assistance where it was not needed previously. This creates confusion and further irritates the customer when they arrive at the Workforce Center expecting the same and find out about theShow MoreRelatedCases of Multiple Provid ers of Agricultural Extension Service in Bangladesh833 Words   |  3 Pages1.2 Agricultural Extension System: the Bangladesh case In Bangladesh a multitude of agencies from private and public origin offer extension support to the farmers (ASIRP, 2006). Although recent years witness a noticeable change in agricultural extension service providers, the public institutions still remain the dominant. The new entrants to the field include non-governmental organizations (NGOs), the private sector agribusiness enterprises and grass-root institutions eg. Self-Help and micro-creditRead MoreHealthcare Financing : Health Care Financing Essay1622 Words   |  7 Pagesfunding of health expenditures is contributed by the government (33%), social health insurance (25%) while private health expenditure and out of pocket payments account for 22%. [15] Sources of funding of health expenditures in Nigeria include; government budgetary allocations at Federal, State and Local government levels, loans and grants, health insurance, private sector contributions and out of pocket expenses. In 2013, the Federal government budgeted 270 billion Naira for the health sector; representingRead MoreHealthcare Technology Assessment1154 Words   |  5 Pagesproviders, insurers, and government healthcare insurance agencies all have workflows defined to covering expenses and costs (Snyder, Paulson, 2002). 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When Polaroid first started their company, they planned to introduce new applications for polarised lightRead MoreThe And Social Issues ( Brammer Quot )1564 Words   |  7 Pagesassert that industry visibility might be related to environmental level, financial and production risk, or the number of customer, the total of employment, the amount of revenue, or taxes of an industry. Therefore, an industry which faced a stronger institutional pressure might have a higher level of commitment on socially responsible behaviour toward stakeholders (I.e. government, consumers and NGO). Accordingly, a related diversified firm, which operates in a lower industry’s visibility, has a lower

Pharmacology for Medical and Biological Research -myassignmenthelp

Question: Discuss about thePharmacology for Medical and Biological Research. Answer: Responsible for Ang II generation Angiotensin-converting enzyme (ACE) generates the production of Angiotensin II (Ang II) that mediates the renin-angiotensin-system (RAS) effects in the body (Becari et al., 2011). On the other hand, Elastase-2 (ELA-2) which is a chymotrypsin-serine protease elastase family member 2A alternatively generates the production of Ang II in the arteries of rats. RAS activation is accelerated after myocardial infarction, however the mechanisms are unknown that lead to Ang II generaton in resistance arteries (Ahmad et al., 2011). Therefore, the paper by Becari et al., (2017) deals with the study of Elastase-2 (ELA-2) activity contributing to increased Angiotensin II (Ang II) formation in resistant arteries and modulation of cardiac function after myocardial infarction (MI). They hypothesized that ELA-2 is responsible for the generation of Ang II and leads to cardiac damage in mice and MI. The result studies showed the first evidence for the hypothesis that ELA-2 is responsible for the formati on of Ang II in the resistance arteries that is modulated to cardiac function after MI. This illustrates that ELA-2 is responsible for the ACE-independent dysregulation of RAS. Techniques used Genotyping The tail tissue genomic DNA was obtained and amplification of the target gene by Polymerase Chain Reaction (PCR). Myocardial infarction was induced by ventral midline skin incision. They were killed by Carbon dioxide (CO2) inhalation after 4 weeks of MI surgery. Echocardiography Fractional shortening and ejection fraction was calculated for the systolic function of left ventricle (LV). Histology Mesenteric arterial bed removal was done and heart was harvested to calculate the infarct size and heart sections were analysed by video microscopy software Leica Qwin. Randomization, group size or blinding Randomization was done to MI or sham surgery in groups; sham WT, ELA-2 KO and MI ELA-2 KO through six independent experiments and data was analysed. Statistical analysis and normalization Log transformation was done to analyse the Ang I and Ang II concentration effect curves and data was analysed through nonlinear regression. Maximum contractile and PD2 values were obtained and two-way ANOVA was done for the statistical analysis. (Table 1- techniques used) Results: Echocardiographic analysis The heart images showed that in WT animals, there was a significantly large LV diameter than ELA-2 KO mice during the events of diastole and systole (4.1 0.03 vs. 3.7 0.07 mm, P 0.05, respectively).This reduction of LV diameter was not observed in infracted mice. The assessment of cardiac function showed that there was decrease in MI and in the ejection fraction in both the strains of infracted and ELA-KO mice. Sham-ELA-2 KO mice showed a lower stroke volume and cardiac output as compared to WT mice. There was decreased cardiac output and stroke volume in WT mice as compared to ELA-2 KO mice. Uehara et al., (2013) also studied that Ang II is activated by RAS as the final physiological product and strong vasopressor that promote tissue remodelling in heart. This mechanism for cardiovascular remodelling is not known that can be helpful in inhibiting the Ang II formation and for the prevention of cardiovascular remodelling (Groutas, Dou Alliston, 2011). ELA-2 is functional in resistance arteries of mice To confirm the functional analysis of ELA-2 in resistance mice arteries, ELA-2 KP mice were induced by chymostatin and no responses were obtained. However, there was significant attenuation of Ang I-induced maximal response in sham-WT mice. There was a rightward-shift of the concentration curve of Ang I due to chymostatin induction. This data clearly illustrated that Ang II generation was induced by serine proteases in resistance mesenteric arteries of mice and in turn, ELA-2 is the major driving reason for the generation of Ang-II enzyme in the arteries. ELA-2 contribution to Ang-I in mesenteric resistance arteries of mice to MI To confirm the ELA-2 contribution to Ang-I, Ang II and Ang I concentration curves were subjected to MI or sham-surgery. The concentration response curve shifted to left of Ang I with maximum effect in WT mice mesenteric arteries. There was also significant increase in the concentration of Ang I in WT mice as compared sham-Wt mice. This data confirmed that MI is strongly associated with increased RAS activation. Therefore, this paper provided the first evidence for the ELA-2 responsible for Ang II increased activity in mesenteric resistance arteries upon MI. Ang I conversion to Ang II by ACE subjected to MI There was rightward-shift in Ang I concentration response curves of mesenteric arteries when subjected Captopril. In ELA-2 KO mice, there was ACE-independent dysregulation of RAS in MI and it might be in other cardiovascular diseases. There is RAS hyperactivity associated with heart failure and there was significant increase in the RAS expression levels due to MI including myocardium (Santos et al., 2013). In a study conducted by Becari, Oliveira Salgado, (2011) showed that cardiac changes in infracted mice was similar to humans that highlights the importance of ELA-2 as the driving factor for Ang I generation at an increased level. The significance of the study is that the mechanism through which Ang II is converted from Ang I and synthesized in human tissues can be helpful in the pharmacology in inhibiting local Ang II formation and further MI (Thatcher et al., 2014). Therefore, this elucidation of ELA-2 being the contributor to the Ang II formation can be a great strategy for the prevention of cardiovascular diseases and remodelling as in MI. From the above-obtained results, it can be inferred that ELA-2 is the contributor to vascular Ang II increased formation. It may also contribute to the cardiac dysfunctioning after MI. This implies that ELA-2 enzyme is the key player in the ACE-independent RAS dysregulation. This study confirmed that there is increased RAS activation in vascular beds as there was augmented Ang-1 induction in resistance arteries of sham-mice to MI. This is the first evidence provided by this study where MI did not affect the Ang I contractile responses that increased the generation of Ang-II upon MI. There is also significant cardiac sympathovagal balance dysregulation in ELA-2 KO mice along with increased parasympathetic and decreased sympathetic modulation. There was low cardiac output, heart rate, reduced LV and stroke volume that are interesting findings of this study adding to the existing knowledge of overall systemic or autonomic dysregulation in mesenteric nerves. This data indicated that ELA- 2 plays the pivotal role in the peripheral resistance and basal cardiac function. References Ahmad, S., Simmons, T., Varagic, J., Moniwa, N., Chappell, M. C., Ferrario, C. M. (2011). Chymase-dependent generation of angiotensin II from angiotensin-(1-12) in human atrial tissue.PloS one,6(12), e28501. Becari, C., Oliveira, E. B., Salgado, M. C. O. (2011). Alternative pathways for angiotensin II generation in the cardiovascular system.Brazilian Journal of Medical and Biological Research,44(9), 914-919. Becari, C., Silva, M. A., Durand, M. T., Prado, C. M., Oliveira, E. B., Ribeiro, M. S., ... Tostes, R. C. (2017). Elastase?2, an angiotensin II?generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction. British Journal of Pharmacology, 174(10), 1104-1115. Becari, C., Teixeira, F. R., Oliveira, E. B., Salgado, M. C. O. (2011). Angiotensin-converting enzyme inhibition augments the expression of rat elastase-2, an angiotensin II-forming enzyme.American Journal of Physiology-Heart and Circulatory Physiology,301(2), H565-H570. Groutas, W. C., Dou, D., Alliston, K. R. (2011). Neutrophil elastase inhibitors.Expert opinion on therapeutic patents,21(3), 339-354. Santos, R. A., Ferreira, A. J., Verano-Braga, T., Bader, M. (2013). Angiotensin-converting enzyme 2, angiotensin-(17) and Mas: new players of the reninangiotensin system.Journal of Endocrinology,216(2), R1-R17. Thatcher, S. E., Zhang, X., Howatt, D. A., Yiannikouris, F., Gurley, S. B., Ennis, T., ... Cassis, L. A. (2014). Angiotensin-Converting Enzyme 2 Decreases Formation and Severity of Angiotensin IIInduced Abdominal Aortic Aneurysms.Arteriosclerosis, thrombosis, and vascular biology, ATVBAHA-114. Uehara, Y., Miura, S. I., Yahiro, E., Saku, K. (2013). Non-ACE pathway-induced angiotensin II production. Current pharmaceutical design, 19(17), 3054-3059.

Return Essays - Thomas Hardy, The Return Of The Native, Egdon Heath

Return Of The Native The novel, The Return of the Native, explores the clash between the inevitable social change and a traditional way of life. Set in imaginary landscape of Wessex, the story concerns Eustacia Vye, Mrs Yeobright, Thomasin, and Damon Wildeve - and how Clym Yeobright, the returning native of the title, affects each of their destinies, an his own. The brooding menace of Egdon Heath in Dorsetshire opens Hardy's novel of tragic passion. Eustacia Vye, willful and longing for the excitement of city life, awaits her lover on the forbidding moor. She married Clym Yeobright, newly returned from Paris, thinking he would take her there, but Clym is content as the country schoolmaster. With her dreams thwarted and confused circumstances that lead her to believe she has caused the death of Clym's mother, not even her affair with reckless Damon Wildeve can keep her from sinking into the despair that leads to her death by drowning. Once again Hardy creates a masterful net of destiny from which his tragic characters cannot escape. Clym affected each of their lives in a different way. Before returning to Wessex, Thomasin was going to marry Wildeve. But Wildeve and Eustacia secretly liked each other. Mrs. Yeobright wanted Thomasin to marry Clym when he returned. But Thomasin liked Wildeve. So when Clym returned, he fell in love with Eustacia. She also loved Clym, and persuaded Wildeve to marry Thomasin. Then Eustacia and Clym got married. Mrs. Yeobright did not approve of any of these marriages. After a while, Clym's eyesight grew weaker and weaker until he was force to become a spur's cutter. This made Eustacia mad because she thought she would never see Paris now. Suddenly, the feelings Eustacia and Wildeve had for one another grew stronger, and they began seeing each other again. All the while, Tomasin was feeling lonely. Her husband was not spending any time with her. Mrs. Yeobright felt as if she was being cast off by her son. When she went to visit him, but no one would let her in. She died on her way home. Rumors went around that Eustacia would let her in because she had a man in the house with her. So Eustacia left Clym, and went to her grandfather's house. She and Wildeve later decide to run away with each. But before they could live happily ever after together, they died. So in the end, if he had not returned, things may have turned out different. Cylm and Thomasin would have gotten married, and they and Mrs. Yeobright would have moved to Paris. Eustacia and Wild eve Would have also gotten married. The Return of the Native, by Thomas Hardy, achieves the intensity of classical Greek tragedy in its depiction of a pitiable human struggle against relentless fate. The author's somber view of human existence is expressed both in the superb opening description of Egdon Heath and in the tragic lives of Clym Yeobright, the returned native of the heath, his cousin Thomasin, Damon Wildeve, his mother Mrs. Yeobright, and Eustacia

Mugged by Andrew Payne Essay Example

Mugged by Andrew Payne Essay I performed in Mugged by Andrew Payne. I played the character of Taylor who was a deprived boy who has turned into a bully because of the people that he is around. Mugged is a play about six teenagers that are affected by the things around them, two are bullies, two are boys who are good friends that try to act cool and the two girls go along with the bullies. The teenagers are scared of the muggers and this ends up in one of the six being stabbed. In my essay I am going to study the plays of mugged and Blood Brothers and also Billy Elliot. My character of Taylor is a street wise teenager who is one of the school bullies. He victimises people who are quieter and less street wise than him. He is scared of some individuals across the park that they all fear and see as muggers but intimidates those less powerful than him and makes it look like he is not scared when he secretly is. I played the character of Taylor using some techniques such as walking in the way that a teenage boy would walk and also raising the tone of my voice to make me seem a lot more superior and also talking louder than I normally would. We will write a custom essay sample on Mugged by Andrew Payne specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Mugged by Andrew Payne specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Mugged by Andrew Payne specifically for you FOR ONLY $16.38 $13.9/page Hire Writer I tried to base that character of Taylor like the character of Tony Elliot, Billys older brother. The actor who played Tony showed his power and authority by raising his voice and he seemed like the type of person who would break the rules but he was very loyal to the miners on strike by not caving in because he needed the money he continued with his work mates. Although he was over powering when he told Billy to dance on the table he was trying to show compassion that he is only a little boy and should not go to ballet school. I tied to play Taylor as very headstrong but towards the end he was a bit lost in whom he was and what he was doing there and I tried to show that he also had a compassionate side. Playing the part of Taylor in mugged helped me to understand how a person like this would relate to the settings around him and also the other characters on the stage. The part of Taylor is a bit like the character of Sammy Johnstone in Blood Brothers because even know they are not the main character in the play they are still a character that has a lot of impact on the other characters and of the outcome at the end of the production. The characters of Sammy, Tony and Taylor have an outcome on the productions that I have used above because they cause life changing situation and in the plays Blood Brothers and Mugged someone ends up dying and Tony changes the decisions that are made but does not affect the play as much. The set of mugged is very simple compared to the sets of Blood Brothers and Billy Elliot. The set of Billy Elliot is the main background of the village miners hall and the bedroom and house was brought in by hydraulics under the stage and other things are brought in by the cast and crew. In Blood brothers the main setting in the first act is the old council buildings on the stage right and on the stage left a posh middle class house. In the second act it changes to some better presented council houses again the other parts of the stage are brought in by the cast and crew. The setting of Mugged was very simple because we performed it in our school so we had two park benches and a bin in between the two benches and that was it so that the set did not distract the audience form the performers. Also this is all that we needed for our play to make it look realistic. Our costumes were very simple me, Sian who played Leon, Allanah who played Marky and Kerry who played Dig wore jogging bottoms and a zip up hoddy to look like the style of people who were trying to be. Penny who played Mel and Georgina who played Soph wore there school skirts and a coat to look like slutty girls. In Billy Elliot each character had more than one costume because the play was over a few months the only person who wore the same costume was Mrs Elliot because she only was on a few times and she was dead so she did not change. Also in Blood Brothers they were a few different costumes because they are playing people over 10 years apart so they have different costumes to show the differences in age and also how they have grown up. Most productions on the West end and in most theatres are different to ours because they have people making the costumes and doing the makeup but because we only did it in school we did not have to do much to make it look good because people do not expect it to look good because it is only armature dramatics so we would not have very good costumes and also we would not have a very complex set. The theme of Mugged is mainly Friendship and who to make friends with and how friends act towards each other. Our play is also about peer pressure which ties in with the plot of both Blood Brothers and Billy Elliot because in both of these plays there is a lot of peer pressure. In Billy Elliot there is peer pressure because the miners are pressurised to stay on strike but Billys dad decided that he would break it for his son to go to ballet school. And in Blood brothers Sammy and his gang pressured Mickey. Linda and Eddie into things that they dont want to do and end up in trouble.

Word Choice Farther vs. Further - Proofread My Paper

Word Choice Farther vs. Further - Proofread My Paper Word Choice: Farther vs. Further â€Å"Farther† and â€Å"further† mean the same thing, right? Well, sometimes. But in American English we distinguish between these terms in some contexts, so it’s worth knowing the difference. This is especially true in academic and other formal writing, where precision is vital. To find out how these terms should be used, learn the traditional distinction below. Farther (Physical Distance) Although these terms are increasingly used interchangeably, technically, â€Å"farther† is reserved for discussing physical distances. As such, we might say: The library is farther down the road from here than the post office. Here, â€Å"farther† simply means â€Å"at a greater distance,† since it’s the comparative form of â€Å"far.† The same rule applies to â€Å"farthest,† which means â€Å"at the greatest physical distance.† It might be worth distinguishing between farther and a father, while were at it. Further (Metaphorical Distance) So, how does â€Å"further† differ? When referring to physical distance, not at all. As such, it would be correct to say: The library is further down the road from here than the post office. This means exactly the same thing as using â€Å"farther† in the same sentence. However, â€Å"further† is also used for figurative or non-physical distances. For instance, if we were referring to something that happens at a later point in time, we’d have to use â€Å"further†: Proofreading happens further along in the publication process than editing. Likewise, â€Å"further† is used when referring to things such as how far prices rise and fall or the point we’ve reached in a book: Before you read any further, stop and reflect on the themes in this chapter. If referring to the greatest figurative distance, â€Å"furthest† is the correct term to use. This â€Å"metaphorical† sense of â€Å"further† is also reflected in its use to mean â€Å"additional,† such as when we say that something requires â€Å"further study.† In all of these cases, using â€Å"farther† would be incorrect according to the conventional distinction. Farther or Further? The good news is that â€Å"further† is usually correct regardless of context. Throw in the fact that â€Å"farther† is much less common these days, as shown in this n-gram chart, and you might be safer using â€Å"further† for all senses of the word. Farther or further? However, if you want to ensure in your work, it’s a good idea to maintain the traditional distinction between â€Å"farther† and â€Å"further.† Remember: Farther = At a greater physical distance Further = At a greater figurative or non-physical distance

Nutrition Discussions 6-9 Assignment Example | Topics and Well Written Essays - 500 words - 1

Nutrition Discussions 6-9 - Assignment Example ery important information on any form of diagnosed and any undiagnosed abnormality in the growth, overweight, obesity, development and the many risk factors prone to its citizens. Environmental factors are put into consideration as to determine what are the citizens are exposed to. These surveys are necessary as they are conducted to determine the missing link in the welfare of the citizens. This includes quality check of life from the young to the old. This must be encouraged year after year and all the necessary information dispensed to the nation at large including the social media facilities at our countries disposal, (Nieman, National dietary and Nutrition Surveys). Energy is measured in values termed as kilocalories (kcals).This energy is obtained from food that human beings consume. A lot of research has been done to determine the caloric value in the various type of food human take. To determine the food caloric value, one needs to classify the content of food in terms of carbohydrate, fat and protein values. It has been noted that carbohydrates give 4kcal per given gram (g), proteins giving the same value of 4 kcal and fats having recorded the highest at 9 kcal, (Stanfield, Meeting Energy Needs in Nutrition and Diet Therapy: Self-Instructional Modules). The quest to determine energy needs is done on three major classifications that is activity, thermic effect on food, and basal metabolic rate. The basal metabolism is the energy required to drive the vital life procedures in a human being and is positive or negatively affected by; physiological status, body temperature, body composition, age and sex. Physical activity burns out calories while mental work does much lesser. Production of heat after having meals brings thermic effect; this largely depends on the type of food taken, (Stanfield, Meeting Energy Needs in Nutrition and Diet Therapy: Self-Instructional Modules). This energy intake needs to be balanced. It’s very important to maintain the energy